Phenotypes Associated with This Genotype

Genotype
MGI:4843963

• Allelic Composition: Pdpn^tm1(cre)Mlkn/Pdpn^tm1(cre)Mlkn
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:162815 )

N • platelets form aggregates under flow when plated on microvascular endothelial cells (LEC)

intestinal edema ( J:162815 )

• in neonates

immune system

abnormal lymphatic vessel morphology ( J:162815 )

• at E11.5, mice exhibit lymph sacs filled with blood unlike in wild-type mice

• at E14.5, mice exhibit blood-filled cutaneous lymphatics unlike in wild-type mice

• neonates exhibit blood-filled mesenteric lymphatics unlike in wild-type mice

digestive/alimentary system

intestinal edema ( J:162815 )

• in neonates