Phenotypes Associated with This Genotype

Genotype
MGI:4840474

• Allelic Composition: Sufu^tm1Hui/Sufu^tm1Hui; Tg(Fabp4-cre)1Rev/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

adipose tissue phenotype ( J:166285 )

N • brown adipose tissue is normal

abnormal white adipose tissue morphology ( J:166285 )

decreased subcutaneous adipose tissue amount ( J:166285 )

• subcutaneous white adipose tissue

decreased white adipose tissue amount ( J:166285 )

• reduced white adipose tissue detected by MRI

• particularly perigonadal, mesenteric, and subcutaneous adipose tissue

abnormal white fat cell morphology ( J:166285 )

decreased white fat cell number ( J:166285 )

decreased white fat cell size ( J:166285 )

abnormal white adipose tissue physiology ( J:166285 )

• stromal vascular cell fractions from white adipose tissue cannot be stimulated to differentiate

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:166285 )

N • normal glucose tolerance and insulin sensitivity

integument

decreased subcutaneous adipose tissue amount ( J:166285 )

• subcutaneous white adipose tissue