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Phenotypes Associated with This Genotype
Genotype
MGI:4840319
Allelic
Composition		 Bcl2l1tm1Dlo/Bcl2l1tm1.1Mam
Tg(Aicda-cre)9Mbu/0
Genetic
Background		 B6.Cg-Bcl2l1tm1Dlo/Bcl2l1tm1.1Mam Tg(Aicda-cre)9Mbu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcl2l1tm1.1Mam mutation (0 available); any Bcl2l1 mutation (106 available)
Bcl2l1tm1Dlo mutation (0 available); any Bcl2l1 mutation (106 available)
Tg(Aicda-cre)9Mbu mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:166069 )
N
• affinity maturation among NP-reactive B cells and germinal cell formation are normal
decreased IgG1 level ( J:166069 )
• following immunization with NP-KLH, the frequency of NP-specific IgG1 in the bone marrow compared to in similarly treated wild-type mice

hematopoietic system
decreased IgG1 level ( J:166069 )
• following immunization with NP-KLH, the frequency of NP-specific IgG1 in the bone marrow compared to in similarly treated wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory