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Phenotypes Associated with This Genotype
Genotype
MGI:4840263
Allelic
Composition		 L3mbtl1tm1.1Haho/L3mbtl1tm1.1Haho
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
L3mbtl1tm1.1Haho mutation (2 available); any L3mbtl1 mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:166180 )
N
• mice exhibit normal life span and survival after sublethal irradiation

nervous system
nervous system phenotype ( J:166180 )
N
• mice exhibit normal central nervous system development and function

hematopoietic system
hematopoietic system phenotype ( J:166180 )
N
• mice exhibit normal hematopoiesis and lymphopoiesis

cellular
cellular phenotype ( J:166180 )
N
• embryonic stem cells exhibit normal cell cycle progression, global chromatin density, and histone methylation
• mouse embryonic fibroblasts exhibit normal cell cycle arrest in response to irradiation

immune system
immune system phenotype ( J:166180 )
N
• mice exhibit normal hematopoiesis and lymphopoiesis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory