Phenotypes for Drd2 Drd3 MGI:4839981 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Drd2^tm1Ebo/Drd2^tm1Ebo Drd3^tm1Dac/Drd3^tm1Dac
Genetic Background	involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Drd2^tm1Ebo mutation (0 available); any Drd2 mutation (68 available)
Drd3^tm1Dac mutation (2 available); any Drd3 mutation (59 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal behavior ( J:96229 )

• in a non-selective attention test, mice exhibit lower scanning times (measured by duration of individual rearing episodes) during the first part of the test compared with wild-type mice

abnormal emotion/affect behavior ( J:96229 )

• mice exhibit a reduction in defecation score, as an emotional index, compared with wild-type mice

decreased vertical activity ( J:96229 )

• frequency and duration

decreased locomotor activity ( J:96229 )

digestive/alimentary system

abnormal defecation ( J:96229 )

• mice exhibit a reduction in defecation score, as an emotional index, compared with wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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