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Phenotypes Associated with This Genotype
Genotype
MGI:4839091
Allelic
Composition		 Fbn1tm2.1Lysa/Fbn1tm2.1Lysa
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbn1tm2.1Lysa mutation (0 available); any Fbn1 mutation (171 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:165897 )
N
• mice exhibit normal lifespan unlike mice homozygous for other Fbn1 mutations

cardiovascular system
cardiovascular system phenotype ( J:165897 )
N
• aortic elastic fiber morphology is normal

integument
integument phenotype ( J:165897 )
N
• mice exhibit normal cutaneous microfibril morphology

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory