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Phenotypes Associated with This Genotype
Genotype
MGI:4838615
Allelic
Composition		 Smotm2Amc/Smotm2Amc
Tg(Gfap-cre)73.12Mvs/0
Genetic
Background		 involves: 129X1/SvJ * BALB/c * C57BL/6NHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smotm2Amc mutation (2 available); any Smo mutation (44 available)
Tg(Gfap-cre)73.12Mvs mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:165495 )
N
• mice exhibit normal forebrain morphology and cytoarchitecture
• the number of astrocytes in the cortex is normal
astrocytosis ( J:165495 )
• mild in the cortex

cellular
astrocytosis ( J:165495 )
• mild in the cortex

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory