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Phenotypes Associated with This Genotype
Genotype
MGI:4838530
Allelic
Composition		 Myh9tm5Rsad/Myh9tm5Rsad
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myh9tm5Rsad mutation (1 available); any Myh9 mutation (219 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal leukocyte migration ( J:164684 )
• CD3 and CD28 antibody-activated T cells transfected with a retroviral cre-GPF exhibit impaired intra-lymph node migration compared with cells transfected with only GFP
abnormal T cell physiology ( J:164684 )
• CD3 and CD28 antibody-activated T cells transfected with a retroviral cre-GPF exhibit impaired intra-lymph node migration compared with cells transfected with only GFP

cellular
abnormal leukocyte migration ( J:164684 )
• CD3 and CD28 antibody-activated T cells transfected with a retroviral cre-GPF exhibit impaired intra-lymph node migration compared with cells transfected with only GFP

hematopoietic system
abnormal leukocyte migration ( J:164684 )
• CD3 and CD28 antibody-activated T cells transfected with a retroviral cre-GPF exhibit impaired intra-lymph node migration compared with cells transfected with only GFP
abnormal T cell physiology ( J:164684 )
• CD3 and CD28 antibody-activated T cells transfected with a retroviral cre-GPF exhibit impaired intra-lymph node migration compared with cells transfected with only GFP

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory