Phenotypes Associated with This Genotype

Genotype
MGI:4837486

• Allelic Composition: Rassf1^tm1.1Brd/Rassf1^tm1.1Brd; Tg(Myh6-cre)2182Mds/0
• Genetic Background: involves: 129S7/SvEvBrd * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

decreased response of heart to induced stress ( J:165327 )

• following pressure overload hypertrophy, fibrosis and cardiomyocyte apoptosis are decreased and heart function is improved compared to wild-type controls

• in the absence of pressure overload, gross cardiac morphology is similar to controls

homeostasis/metabolism

decreased response of heart to induced stress ( J:165327 )

• following pressure overload hypertrophy, fibrosis and cardiomyocyte apoptosis are decreased and heart function is improved compared to wild-type controls

• in the absence of pressure overload, gross cardiac morphology is similar to controls