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Phenotypes Associated with This Genotype
Genotype
MGI:4837221
Allelic
Composition		 Gata3tm1Jfz/Gata3tm1Jfz
Tg(Fev-cre)1Esd/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata3tm1Jfz mutation (0 available); any Gata3 mutation (31 available)
Tg(Fev-cre)1Esd mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal Raphe nucleus morphology ( J:165266 )
• decrease in the number of Tph immunoreactive cells in the dorsal Raphe nucleus

homeostasis/metabolism
decreased serotonin level ( J:165266 )
• in the dorsal Raphe nucleus

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory