Phenotypes for Smn1 MGI:4836986 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Smn1^tm1Msd/Smn1^tm1.1Dscd
Genetic Background	involves: 129S/SvEv * 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smn1^tm1.1Dscd mutation (0 available); any Smn1 mutation (86 available)
Smn1^tm1Msd mutation (37 available); any Smn1 mutation (86 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased grip strength ( J:164889 )

decreased vertical activity ( J:164889 )

• at 60 days

decreased locomotor activity ( J:164889 )

• at 60 days

nervous system

nervous system phenotype ( J:164889 )

N	• mice exhibit normal neuromuscular junctions morphology and neuromuscular transmissions

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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