Phenotypes Associated with This Genotype

Genotype
MGI:4836582

• Allelic Composition: Plaur^tm1Jld/Plaur^tm1Jld
• Genetic Background: B6.129P2-Plaur^tm1Jld

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

chronic inflammation ( J:164542 )

• chronic inflammation is secondary to fibrin deposition

increased inflammatory response ( J:164542 )

• in the liver

• in the trachea of 3 in 7 mice

• however, leukocyte accumulation in standard models of inflammation is normal

liver inflammation ( J:164542 )

• the number of inflammatory foci is increased compared to in wild-type mice

trachea inflammation ( J:164542 )

• 3 of 7 mice exhibit mild to moderate inflammation of the trachea unlike wild-type mice

respiratory system

trachea inflammation ( J:164542 )

• 3 of 7 mice exhibit mild to moderate inflammation of the trachea unlike wild-type mice

liver/biliary system

liver inflammation ( J:164542 )

• the number of inflammatory foci is increased compared to in wild-type mice

liver fibrosis ( J:164542 )

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:164542 )

N • skin wound healing is normal