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Phenotypes Associated with This Genotype
Genotype
MGI:4834589
Allelic
Composition		 Tardbptm1.1Pcw/Tardbp+
Tg(CAG-cre/Esr1*)5Amc/0
Genetic
Background		 involves: 129 * C57BL/6 * CBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tardbptm1.1Pcw mutation (1 available); any Tardbp mutation (60 available)
Tg(CAG-cre/Esr1*)5Amc mutation (9 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:164406 )
• after cre induction by tamoxifen, mice show decrease in body weight relative to controls

adipose tissue
abnormal brown fat cell morphology ( J:164406 )
• absence of fatty acid vacuoles in adipocytes in interscapular brown fat is detected
abnormal white fat cell morphology ( J:164406 )
• reduction of fatty acid vacuoles in adipocytes in subcutaneous fat is detected

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory