Analysis Tools
immune system
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• IgE monoclonal anti-DNP antibody primed mast cells are incapable of significant degranulation unlike similarly treated wild-type cells
• however, cells exhibit normal
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• osteoclasts exhibit impaired bone remodeling compared with wild-type cells
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• mice are resistant to IgE-mediated anaphylaxis unlike wild-type mice
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nervous system
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• oligodendrocyte precursor cells fail to differentiate in the presence of IgG or anti-Fcrg antibodies unlike wild-type cells
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• at P10
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• at P10
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skeleton
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• osteoclasts exhibit impaired bone remodeling compared with wild-type cells
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• metaphyseal bone trabecules are irregularly distributed compared to in wild-type mice
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hematopoietic system
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• IgE monoclonal anti-DNP antibody primed mast cells are incapable of significant degranulation unlike similarly treated wild-type cells
• however, cells exhibit normal
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• bone marrow leukocytes exhibit defective motility, progenitor cell expansion, homing, and mobilization by colony-stimulating factor (G-CSF) and increased cell adhesion compared with wild-type cells
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• osteoclasts exhibit impaired bone remodeling compared with wild-type cells
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cellular
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• oligodendrocyte precursor cells fail to differentiate in the presence of IgG or anti-Fcrg antibodies unlike wild-type cells
|
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• at P10
|
|
• IgE monoclonal anti-DNP antibody primed mast cells are incapable of significant degranulation unlike similarly treated wild-type cells
• however, cells exhibit normal
|
