Phenotypes Associated with This Genotype

Genotype
MGI:4834183

• Allelic Composition: Ptger1^tm1Sna/Ptger1^tm1Sna
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

decreased incidence of tumors by chemical induction ( J:95533 )

• following azoxymethane exposure the incidence of colon tumors is decreased

decreased tumor growth/size ( J:95533 )

• following azoxymethane exposure the colon tumor volume is decreased

• in azoxymethane induced colon tumors cell proliferation is decreased and apoptosis is increased

homeostasis/metabolism

abnormal physiological response to xenobiotic ( J:95533 )

• body weights are significantly greater at 35 and 50 weeks after azoxymethane exposure

decreased incidence of tumors by chemical induction ( J:95533 )

• following azoxymethane exposure the incidence of colon tumors is decreased

growth/size/body

increased body weight ( J:95533 )

• body weights are significantly greater at 35 and 50 weeks after azoxymethane exposure