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Phenotypes Associated with This Genotype
Genotype
MGI:4833694
Allelic
Composition		 Cacna1atg-rol/Cacna1atg
Genetic
Background		 involves: C3H * C57BL/6 * DBA/2J * SIII
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacna1atg mutation (1 available); any Cacna1a mutation (116 available)
Cacna1atg-rol mutation (1 available); any Cacna1a mutation (116 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:14882 )
N
• normal life span

behavior/neurological
behavior/neurological phenotype ( J:14882 )
N
• mutants do not exhibit epileptiform seizures that are seen in single homozygous Cacna1atg mice
abnormal gait ( J:14882 )
• develop wobbly gait that is similar to that of single homozygous Cacna1atg-rol but more severe than in single homozygous Cacna1atg mice

nervous system
abnormal nervous system morphology ( J:14882 )
• neuromuscular disorder appears at 2 weeks of age, at a similar time frame as in single homozygous Cacna1atg-rol mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory