Mouse Genome Informatics
ot
    Dp(2Csrp2bp-6330439K17Rik)1Bra/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       

Eye abnormalities in Dp(2Csrp2bp-6330439K17Rik)1Bra/0 mice

vision/eye
N
• mice backcrossed to C57BL/6 for 3 generations do not exhibit the Corneal Dystrophy, Posterior Polymorphous, 1 (PPCD1) phenotype (J:164007)
• posterior and anterior
• mice exhibit corneal haze, neovascularization, ulcers, and scarring unlike wild-type mice
• the anterior chamber is deep and enlarged compared to in wild-type mice
• mice exhibit lens subluxation unlike wild-type mice

cardiovascular system

Mouse Models of Human Disease
OMIM IDRef(s)
Corneal Dystrophy, Posterior Polymorphous, 1; PPCD1 122000 J:164007