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Phenotypes Associated with This Genotype
Genotype
MGI:4830892
Allelic
Composition
Dp(2Csrp2bp-Dzank1)1Bra/0
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dp(2Csrp2bp-Dzank1)1Bra mutation (1 available); any Dp(2Csrp2bp-Dzank1)1Bra mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Eye abnormalities in Dp(2Csrp2bp-Dzank1)1Bra/0 mice

vision/eye
N
• mice backcrossed to C57BL/6 for 3 generations do not exhibit the Corneal Dystrophy, Posterior Polymorphous, 1 (PPCD1) phenotype
• mice exhibit corneal haze, neovascularization, ulcers, and scarring unlike wild-type mice
• the anterior chamber is deep and enlarged compared to in wild-type mice
• mice exhibit lens subluxation unlike wild-type mice

cardiovascular system

Mouse Models of Human Disease
OMIM ID Ref(s)
Corneal Dystrophy, Posterior Polymorphous, 1; PPCD1 122000 J:164007


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory