Phenotypes for Nodal Trim33 MGI:4830333 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Nodal^tm1Rob/Nodal⁺ Trim33^tm1.2Los/Trim33^tm1.2Los
Genetic Background	involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nodal^tm1Rob mutation (1 available); any Nodal mutation (41 available)
Trim33^tm1.2Los mutation (0 available); any Trim33 mutation (71 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

embryo phenotype ( J:163858 )

N	• the decrease in Nodal expression rescues patterning defects in the extraembryonic ectoderm and mesoderm and the decrease in embryo size that are seen in Trim33 single homozygotes

expanded anterior visceral endoderm ( J:163858 )

• expanded at E6.25

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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