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Phenotypes Associated with This Genotype
Genotype
MGI:4830332
Allelic
Composition		 Ptk7chz/Ptk7+
Vangl2Lp/Vangl2+
Genetic
Background		 involves: A * BALB/cAnN * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptk7chz mutation (2 available); any Ptk7 mutation (59 available)
Vangl2Lp mutation (2 available); any Vangl2 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
spina bifida ( J:163834 )
• 23% exhibit spina bifida or craniorachischisis
craniorachischisis ( J:163834 )
• 23% exhibit spina bifida or craniorachischisis

nervous system
spina bifida ( J:163834 )
• 23% exhibit spina bifida or craniorachischisis
craniorachischisis ( J:163834 )
• 23% exhibit spina bifida or craniorachischisis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory