Phenotypes for Nodal Trim33 MGI:4830331 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Nodal^tm1Rob/Nodal^tm2Rob Trim33^tm1.2Los/Trim33^tm1.2Los
Genetic Background	involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nodal^tm1Rob mutation (2 available); any Nodal mutation (41 available)
Nodal^tm2Rob mutation (0 available); any Nodal mutation (41 available)
Trim33^tm1.2Los mutation (0 available); any Trim33 mutation (76 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

embryo phenotype ( J:163858 )

N	• at E6.25 decrease in Nodal expression rescues patterning defects in the anterior visceral endoderm, extraembryonic ectoderm and mesoderm and the decrease in embryo size that are seen in Trim33 single homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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