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Phenotypes Associated with This Genotype
Genotype
MGI:4830331
Allelic
Composition
Nodaltm1Rob/Nodaltm2Rob
Trim33tm1.2Los/Trim33tm1.2Los
Genetic
Background
involves: 129S/SvEv * 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nodaltm1Rob mutation (1 available); any Nodal mutation (41 available)
Nodaltm2Rob mutation (0 available); any Nodal mutation (41 available)
Trim33tm1.2Los mutation (0 available); any Trim33 mutation (71 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
N
• at E6.25 decrease in Nodal expression rescues patterning defects in the anterior visceral endoderm, extraembryonic ectoderm and mesoderm and the decrease in embryo size that are seen in Trim33 single homozygotes


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory