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Phenotypes Associated with This Genotype
Genotype
MGI:4830328
Allelic
Composition		 Smad4tm1Rdp/Smad4tm1.1Rdp
Trim33tm1.1Los/Trim33tm1.2Los
Tg(CAG-cre)13Miya/0
Genetic
Background		 involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smad4tm1.1Rdp mutation (0 available); any Smad4 mutation (43 available)
Smad4tm1Rdp mutation (0 available); any Smad4 mutation (43 available)
Tg(CAG-cre)13Miya mutation (1 available)
Trim33tm1.1Los mutation (0 available); any Trim33 mutation (71 available)
Trim33tm1.2Los mutation (0 available); any Trim33 mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal embryo development ( J:163858 )
• identical to mice null for Smad4 alone
absent anterior visceral endoderm ( J:163858 )
• not induced at E5.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory