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Phenotypes Associated with This Genotype
Genotype
MGI:4830267
Allelic
Composition		 Col2a1tm1.1Ksec/Col2a1+
Nodaltm1Rob/Nodal+
Genetic
Background		 involves: 129S/SvEv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col2a1tm1.1Ksec mutation (0 available); any Col2a1 mutation (73 available)
Nodaltm1Rob mutation (2 available); any Nodal mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
abnormal head morphology ( J:163739 )
• the frequency of head abnormalities is not significantly different from Col2a1tm1.1Ksec single heterozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory