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Phenotypes Associated with This Genotype
Genotype
MGI:4829961
Allelic
Composition		 Esr1tm1.1Pws/Esr1tm1.1Pws
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Esr1tm1.1Pws mutation (0 available); any Esr1 mutation (67 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal reproductive system morphology ( J:163783 )
• authors state that mice exhibit similar reproductive phenotypes observed in Esr1tm1.1Mma homozygotes

cardiovascular system
abnormal vascular wound healing ( J:163783 )
• following arterial denudation, mice exhibit decreased estrogen and estrogen-dendrimer conjugate (EDC)-stimulated reendothelialization compared with similarly treated wild-type mice

homeostasis/metabolism
abnormal vascular wound healing ( J:163783 )
• following arterial denudation, mice exhibit decreased estrogen and estrogen-dendrimer conjugate (EDC)-stimulated reendothelialization compared with similarly treated wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory