Phenotypes Associated with This Genotype

Genotype
MGI:4822325

• Allelic Composition: Tg(SOD1*G93A)2Gur/0
• Genetic Background: involves: C57BL/6 * FVB/N * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

decreased heart rate ( J:137769 )

• heart rate reduction

ventricular premature beat ( J:137769 )

• more premature ventricular contractions

nervous system

abnormal parasympathetic nervous system physiology ( J:137769 )

• increased parasympathetic activity

• high frequency of atrioventricular block and premature ventricular contractions

homeostasis/metabolism

abnormal enzyme/coenzyme activity ( J:137769 )

• decreased acetylcholinesterase and butyryl cholinesterase activities in the hearts