Phenotypes for App MGI:4822179 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	App^tm3.2Umu/App^tm2Cwe
Genetic Background	involves: 129P2/OlaHsd * BALB/cJ * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
App^tm2Cwe mutation (0 available); any App mutation (118 available)
App^tm3.2Umu mutation (0 available); any App mutation (118 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased grip strength ( J:163059 )

• displayed a pronounced and significant difference in grip strength compared to wild-type mice

growth/size/body

decreased body weight ( J:163059 )

• body weight is reduced by about 10.6%

nervous system

decreased brain weight ( J:163059 )

• wet brain weight is reduced

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/28/2026 MGI 6.24