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Phenotypes Associated with This Genotype
Genotype
MGI:4822146
Allelic
Composition
l11Jus16/l11Jus16
Genetic
Background
involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
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phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• mice exhibit L-loop ventricles and situs inversus in the heart
• in 3 of 17 mice
• observed in 2 of 17 mutant mice
• AVSD with dextrocardia is seen in 2 of 17 mice
• AVSD with levocardia is seen in 3 of 17 mice
• mutant mice develop atrioventricular septal defects with complete penetrance and variable expressivity
• 1 in 17 mice exhibit muscular ventricular septal defect

growth/size/body
• mutant mice exhibit situs inversus in the heart


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/15/2017
MGI 6.10
The Jackson Laboratory