About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4822145
Allelic
Composition
Dnah11avc4/Dnah11avc4
Genetic
Background
involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnah11avc4 mutation (0 available); any Dnah11 mutation (102 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• 2 of 25 mice exhibit hypoplastic pulmonary artery
• 3 of 25 mice exhibit interrupted aortic arch
• some mutant mice develop atrial septal defects of the primum type
• all mice exhibit septal defects with expressivity varying from primum atrial septal defect to complete AVSD
• some mutant mice develop atrioventricular septal defects of the complete common atrioventricular canal type
• approximately half of affected mutants exhibit unbalanced hypoplastic right ventricle


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/21/2017
MGI 6.08
The Jackson Laboratory