About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4822145
Allelic
Composition
avc4/avc4
Genetic
Background
involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• 2 of 25 mice exhibit hypoplastic pulmonary artery (J:163196)
• 2 of 25 mice exhibit hypoplastic pulmonary artery (J:163196)
• 3 of 25 mice exhibit interrupted aortic arch (J:163196)
• 3 of 25 mice exhibit interrupted aortic arch (J:163196)
• some mutant mice develop atrial septal defects of the primum type (J:163196)
• some mutant mice develop atrial septal defects of the primum type (J:163196)
• all mice exhibit septal defects with expressivity varying from primum atrial septal defect to complete AVSD (J:163196)
• all mice exhibit septal defects with expressivity varying from primum atrial septal defect to complete AVSD (J:163196)
• some mutant mice develop atrioventricular septal defects of the complete common atrioventricular canal type (J:163196)
• some mutant mice develop atrioventricular septal defects of the complete common atrioventricular canal type (J:163196)
• approximately half of affected mutants exhibit unbalanced hypoplastic right ventricle (J:163196)
• approximately half of affected mutants exhibit unbalanced hypoplastic right ventricle (J:163196)

Mouse Models of Human Disease
OMIM ID Ref(s)
Atrioventricular Septal Defect; AVSD 606215 J:163196


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/26/2016
MGI 6.02
The Jackson Laboratory