Phenotypes for Apoe Egr1 MGI:4821395 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Apoe^tm1Unc/Apoe^tm1Unc Egr1^tm1Jmi/Egr1^tm1Jmi
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoe^tm1Unc mutation (35 available); any Apoe mutation (164 available)
Egr1^tm1Jmi mutation (1 available); any Egr1 mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal susceptibility to atherosclerosis ( J:96665 )

• 2.5 fold decrease in lesions at 14 weeks of age compared to Apoe^{tm1Unc/tmiUnc}

• 7 fold difference in lesion numbers at 24 weeks of age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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