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Phenotypes Associated with This Genotype
Genotype
MGI:4821285
Allelic
Composition
Dll1tm1Gos/Dll1+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dll1tm1Gos mutation (2 available); any Dll1 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• in female but not male mice
• a non-significant reduction

homeostasis/metabolism
• Background Sensitivity: when normalized to individual body weight, female mice on a 129 background exhibit increased metabolized energy while male mice exhibit only a tendency compared with wild-type mice whereas on a congenic C3 background only male mice exhibit increased metabolized energy compared with wild-type mice

growth/size/body
• mice fasted for 2 days exhibit a greater loss of body weight compared with similarly treated wild-type mice

skeleton
• similar to on a C3 background, mice exhibit abnormal bone mineral density compared with wild-type mice

hematopoietic system
• in female but not male mice
• a non-significant reduction


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory