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Phenotypes Associated with This Genotype
Genotype
MGI:4820805
Allelic
Composition		 Rettm2(RET)Heno/Rettm1Cos
Tg(CAG-cre/Esr1*)5Amc/0
Genetic
Background		 involves: 129S/Sv * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rettm1Cos mutation (2 available); any Ret mutation (52 available)
Rettm2(RET)Heno mutation (0 available); any Ret mutation (52 available)
Tg(CAG-cre/Esr1*)5Amc mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal enteric ganglia morphology ( J:135153 )
• at E15.5 a nearly complete elimination of the enteric ganglia in the colon when treated with 4-OHT

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory