Phenotypes Associated with This Genotype

Genotype
MGI:4819594

• Allelic Composition: Tg(Thy1-APPDutch)#Jckr/0; Tg(Thy1-PSEN1*G384A)45Jckr/0
• Genetic Background: involves: C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

amyloid beta deposits ( J:162531 )

homeostasis/metabolism

amyloidosis ( J:162531 )

• massive parenchymal amyloidosis is observed throughout the entire brain with the exception of the cerellebum

• modest vascular amyloid also present

amyloid beta deposits ( J:162531 )