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Phenotypes Associated with This Genotype
Genotype
MGI:4819169
Allelic
Composition		 Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+
Trp53bp2tm2Xlu/Trp53bp2tm2Xlu
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(cre/ERT)Brn mutation (1 available); any Gt(ROSA)26Sor mutation (1062 available)
Trp53bp2tm2Xlu mutation (0 available); any Trp53bp2 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
abnormal kidney physiology ( J:162396 )
• in culture primary kidney epithelial cells show a delay in the formation of mature cell junctions

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory