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Phenotypes Associated with This Genotype
Genotype
MGI:4819108
Allelic
Composition
Tg(Thy1-AppDutch)#Jckr/0
Tg(Thy1-PSEN1*G384A)45Jckr/0
Genetic
Background
involves: C57BL/6 * C57BL/6J * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• starting at 12 weeks of age parenchymal amyloid in the neocortex and hippocampus
• at 10 months, massive diffuse and compact parenchymal amyloid are found in virtually all brain regions

homeostasis/metabolism
• starting at 12 weeks of age parenchymal amyloid in the neocortex and hippocampus
• at 10 months, massive diffuse and compact parenchymal amyloid are found in virtually all brain regions

Mouse Models of Human Disease
OMIM ID Ref(s)
Cerebral Amyloid Angiopathy, App-Related 605714 J:92796


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory