About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4819108
Allelic
Composition
Tg(Thy1-AppDutch)#Jckr/0
Tg(Thy1-PSEN1*G384A)45Jckr/0
Genetic
Background
involves: C57BL/6 * C57BL/6J * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• starting at 12 weeks of age parenchymal amyloid in the neocortex and hippocampus
• at 10 months, massive diffuse and compact parenchymal amyloid are found in virtually all brain regions

homeostasis/metabolism
• starting at 12 weeks of age parenchymal amyloid in the neocortex and hippocampus
• at 10 months, massive diffuse and compact parenchymal amyloid are found in virtually all brain regions

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
cerebral amyloid angiopathy DOID:9246 OMIM:105150
OMIM:117300
OMIM:176500
OMIM:605714
J:92796


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/11/2017
MGI 6.10
The Jackson Laboratory