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Phenotypes Associated with This Genotype
Genotype
MGI:4818968
Allelic
Composition
Tg(KRT5-AR)191Cct/0
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• male mice exhibit gray hair in the inguinal region unlike wild-type mice

integument
• male mice exhibit gray hair in the inguinal region unlike wild-type mice
• dihydrotestosterone (DHT)-treated mice subjected to hair stripping exhibit delayed hair regrowth compared with similarly treated wild-type mice
• hair regrowth can be inhibited by dihydrotestosterone (DHT) treatment unlike in wild-type mice
• however, treatment with hydroxyflutamide (OHF) reverses this delay in regrowth

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
androgenic alopecia DOID:0050801 OMIM:109200
OMIM:300710
OMIM:612421
J:159989


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory