Analysis Tools
behavior/neurological
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• decreased forelimb grip strength in comparison to hemizygotes and controls
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• increased motor activity as determined by number of interruptions to photo cell beams
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• reduced rearing activity
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• mice are very active and difficult to handle
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• heightened approach response (approach with a blunt object)
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growth/size/body
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• mice are slender and small
• growth retardation in homozygotes is significantly reduced compared to hemizygotes and controls
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reproductive system
