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Phenotypes Associated with This Genotype
Genotype
MGI:4462168
Allelic
Composition		 Plxna1tm1Kik/Plxna1tm1Kik
Tg(TcraTcrb)425Cbn/?
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plxna1tm1Kik mutation (0 available); any Plxna1 mutation (73 available)
Tg(TcraTcrb)425Cbn mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased T cell proliferation ( J:161856 )
• ova induced proliferative response is much reduced

hematopoietic system
decreased T cell proliferation ( J:161856 )
• ova induced proliferative response is much reduced

cellular
decreased T cell proliferation ( J:161856 )
• ova induced proliferative response is much reduced

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory