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Phenotypes Associated with This Genotype
Genotype
MGI:4461979
Allelic
Composition		 Cbfbtm4Ppl/Cbfb+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cbfbtm4Ppl mutation (0 available); any Cbfb mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
liver/biliary system
pale liver ( J:160522 )
• very pale liver

hematopoietic system
abnormal bone marrow cell morphology/development ( J:160522 )
• no hematopoietic progenitors visible in liver sections
absent megakaryocytes ( J:160522 )
• no megakaryocytes in the liver

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory