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Phenotypes Associated with This Genotype
Genotype
MGI:4460975
Allelic
Composition
Lrrk2tm3.1Shn/Lrrk2tm3.1Shn
Genetic
Background
involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrrk2tm3.1Shn mutation (1 available); any Lrrk2 mutation (156 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
renal/urinary system
• at 20 months, kidneys appear rough and granular, are smaller, weigh less, and are darker than in wild-type mice
• however, kidneys are normal at 10 weeks
• at 20 months
• at 20 months
• in aged mice
• at 20 months

nervous system
N
• mice exhibit normal dopaminergic neurons and dopamine turnover


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory