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Phenotypes Associated with This Genotype
Genotype
MGI:4459500
Allelic
Composition
Nespastm1.1Hju/Nespas+
Genetic
Background
either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6J)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nespastm1.1Hju mutation (0 available); any Nespas mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• when this allele is inherited maternally, mice exhibit do not survive beyond P5

growth/size/body
• when this allele is inherited maternally
• when this allele is inherited maternally, mice exhibit narrow bodies unlike wild-type mice
• when this allele is inherited maternally

cellular
• when this allele is inherited maternally, mice exhibit demethylation and altered expression of genes around the allele compared with wild-type mice
• when this allele is inherited maternally, mice exhibit uniparental phenotypes and demethylation with altered expression of genes around the allele compared with wild-type mice

homeostasis/metabolism
• when this allele is inherited maternally

behavior/neurological
• when this allele is inherited maternally

integument
• when this allele is inherited maternally

Mouse Models of Human Disease
OMIM ID Ref(s)
Pseudohypoparathyroidism, Type IB; PHP1B 603233 J:160293


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory