Mouse Genome Informatics
ht
    Gnas/Nespastm1.1Hju/Gnas+
either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6J)
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• when this allele is inherited maternally, mice exhibit do not survive beyond P5

growth/size
• when this allele is inherited maternally
• when this allele is inherited maternally, mice exhibit narrow bodies unlike wild-type mice
• when this allele is inherited maternally

cellular
• when this allele is inherited maternally, mice exhibit demethylation and altered expression of genes around the allele compared with wild-type mice
• when this allele is inherited maternally, mice exhibit uniparental phenotypes and demethylation with altered expression of genes around the allele compared with wild-type mice

homeostasis/metabolism
• when this allele is inherited maternally

behavior/neurological
• when this allele is inherited maternally

integument
• when this allele is inherited maternally

Mouse Models of Human Disease
OMIM IDRef(s)
Pseudohypoparathyroidism, Type IB; PHP1B 603233 J:160293