mortality/aging
• 23% of mice die between P5 and P31
|
digestive/alimentary system
• mice exhibit decreased stool frequency compared with control mice
|
• mice exhibit wet stool weight and water stool content compared with control mice
|
renal/urinary system
N |
• mice exhibit normal kidney development
|
nervous system
N |
• mice exhibit normal motor innervation
|
• in 8 of 21 mice
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embryo
• colonization of the hindgut with enteric neural crest cells is delayed compared to in wild-type mice
|
growth/size/body
cellular
• colonization of the hindgut with enteric neural crest cells is delayed compared to in wild-type mice
|