Phenotypes Associated with This Genotype

Genotype
MGI:4459059

• Allelic Composition: Ret^{tm3.1(Bcl2l1)Heno}/Ret⁺
• Genetic Background: involves: 129/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:159854 )

N • mice exhibit normal numbers of neurons in the small intestine and colon

decreased neuron apoptosis ( J:159854 )

• enteric neurons are protected from GDNF-induced apoptosis compared with similarly treated wild-type neurons

digestive/alimentary system

digestive/alimentary phenotype ( J:159854 )

N • mice exhibit normal numbers of neurons in the small intestine and colon

cellular

decreased neuron apoptosis ( J:159854 )

• enteric neurons are protected from GDNF-induced apoptosis compared with similarly treated wild-type neurons