About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4459014
Allelic
Composition		 Runx1tm1Yg/Runx1+
Tg(Runx1-GFP)#Itan/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Runx1tm1Yg mutation (2 available); any Runx1 mutation (34 available)
Tg(Runx1-GFP)#Itan mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal dorsal aorta morphology ( J:160791 )
• mice exhibit fewer large GFP+ hematopoietic cells or clusters in the dorsal aorta compared with Tg(Runx1-GFP)#Itan mice

hematopoietic system
abnormal hematopoietic system morphology/development ( J:160791 )
• mice exhibit fewer large GFP+ hematopoietic cells or clusters in the dorsal aorta compared with Tg(Runx1-GFP)#Itan mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory