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Phenotypes Associated with This Genotype
Genotype
MGI:4459011
Allelic
Composition		 Runx1tm1Spe/Runx1tm1Yg
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Runx1tm1Spe mutation (1 available); any Runx1 mutation (34 available)
Runx1tm1Yg mutation (2 available); any Runx1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

hematopoietic system
anemia ( J:160791 )
• severe in the fetal liver at E12.5

cardiovascular system
internal hemorrhage ( J:160791 )
• in the central nervous system at E12.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory