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Phenotypes Associated with This Genotype
Genotype
MGI:4458421
Allelic
Composition
Tfr2tm1.1Anro/Tfr2tm1.1Anro
Genetic
Background
129.Cg-Tfr2tm1.1Anro
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tfr2tm1.1Anro mutation (0 available); any Tfr2 mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• at P14 but reach wild-type hematologic parameters by 10 weeks
• at 10 weeks and 52 weeks

homeostasis/metabolism
N
• at 10 weeks, mice exhibit normal transferrin saturation
• at 10 weeks and 52 weeks
• at 22 and 52 weeks but not in young mice

growth/size/body
• at P14 but reach wild-type weight by 10 weeks

immune system
• at 10 weeks and 52 weeks

liver/biliary system
• at 22 and 52 weeks but not in young mice

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
hemochromatosis type 3 DOID:0111030 OMIM:604250
J:160785


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory