Phenotypes for Lmna Zmpste24 MGI:4457613 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Lmna^tm6Lgf/Lmna⁺ Zmpste24^tm1Sgy/Zmpste24^tm1Sgy
Genetic Background	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmna^tm6Lgf mutation (0 available); any Lmna mutation (84 available)
Zmpste24^tm1Sgy mutation (2 available); any Zmpste24 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

decreased survivor rate ( J:160705 )

• survival is worse than in Zmpste24 single mutants

premature death ( J:160705 )

• survival is worse than in Zmpste24 single mutants

growth/size/body

decreased body weight ( J:160705 )

• smaller than Zmpste24 single mutants

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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