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Phenotypes Associated with This Genotype
Genotype
MGI:4457612
Allelic
Composition		 Lmnatm6Lgf/Lmnatm6Lgf
Zmpste24tm1Sgy/Zmpste24tm1Sgy
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmnatm6Lgf mutation (0 available); any Lmna mutation (84 available)
Zmpste24tm1Sgy mutation (2 available); any Zmpste24 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased survivor rate ( J:160705 )
• survival is worse than in Zmpste24 single mutants
premature death ( J:160705 )
• survival is worse than in Zmpste24 single mutants

growth/size/body
decreased body weight ( J:160705 )
• smaller than Zmpste24 single mutants

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory