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Phenotypes Associated with This Genotype
Genotype
MGI:4456219
Allelic
Composition
Tg(AMH-Fshr*D580Y)#Hht/0
Genetic
Background
involves: FVB/N
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phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• hemorrhagic follicles in 5.9% (1/17) of the mice at 2-3 months of age
• hemorrhagic follicles in 16% (5/31) of the mice at 6-8 months of age
• hemorrhagic follicles in ovaries in 29% (7/24) of the mice at 11-13 months of age
• mature teratoma in one female older than 6 months (1/55)

neoplasm
• mature teratoma in one female older than 6 months (1/55)

cardiovascular system
• hemorrhagic follicles in 5.9% (1/17) of the mice at 2-3 months of age
• hemorrhagic follicles in 16% (5/31) of the mice at 6-8 months of age
• hemorrhagic follicles in ovaries in 29% (7/24) of the mice at 11-13 months of age

endocrine/exocrine glands
• hemorrhagic follicles in 5.9% (1/17) of the mice at 2-3 months of age
• hemorrhagic follicles in 16% (5/31) of the mice at 6-8 months of age
• hemorrhagic follicles in ovaries in 29% (7/24) of the mice at 11-13 months of age
• mature teratoma in one female older than 6 months (1/55)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory