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Phenotypes Associated with This Genotype
Genotype
MGI:4454319
Allelic
Composition		 Patz1tm1.1Welm/Patz1tm1.1Welm
Tg(TcraTcrb)425Cbn/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Patz1tm1.1Welm mutation (0 available); any Patz1 mutation (53 available)
Tg(TcraTcrb)425Cbn mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal T cell subpopulation ratio ( J:158947 )
• slightly higher percentage of CD4+ T cells and correspondingly lower frequency of CD8+ T

immune system
abnormal T cell subpopulation ratio ( J:158947 )
• slightly higher percentage of CD4+ T cells and correspondingly lower frequency of CD8+ T

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory