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Phenotypes Associated with This Genotype
Genotype
MGI:4454315
Allelic
Composition
Rr100tm2.1Welm/Rr100tm2.1Welm
Genetic
Background
involves: 129P2/OlaHsd
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No mouse lines available in IMSR.
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phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• a subpopulation of CD4 SP thymocytes derived in vivo, from transferred E13.5 day livers show surface expression similar to double positive (DP) thymocytes (except lacking CD8 expression)

immune system
N
• no defect is detected in competitive repopulation assays, suggesting the decrease in T cell numbers is a result of decreased body size
• a subpopulation of CD4 SP thymocytes derived in vivo, from transferred E13.5 day livers show surface expression similar to double positive (DP) thymocytes (except lacking CD8 expression)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory